1.Jones G, Zeng L, Kim J. Application of allometric scaling to nanochelator pharmacokinetics. ACS Omega 2023; 8(30):27256-27263. PMID: 37546686. PMCID: PMC10399172.

 

2. Jones G, Zeng L, Kim J. Mechanism-based pharmacokinetic modeling of absorption and disposition of deferoxamine-based nanochelator in rats. Mol Pharm 2023; 20(1):481-490. PMID: 36378830.

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3. Liu J, Lane S, Lall R, Russo M, Farrell L, Debreli Coskun M, Curtin C, Araujo-Gutierrez R, Scherrer-Crosbie M, Trachtenberg BH, Kim J, Tolosano E, Ghigo A, Gerszten RE, Asnani A. Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice. Sci Adv 2022; 8(51):eadc9245. PMID: 36563141.

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4. Jones G, Zeng L, Stiles WR, Park SH, Kang H, Choi HS, Kim J. Pharmacokinetics and tissue distribution of deferoxamine-based nanochelator in rats. NanoMedicine 2022; 17(22):1649-1662. PMID: 36547231.

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5. Menon AV, Liu J, Tsai HP, Zeng L, Yang S, Asnani A, Kim J. Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease. Blood 2022; 139(6):936-941. PMID: 34388243.

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6. Cheng R, Dhorajia V, Kim J, Kim Y. Mitochondrial iron metabolism and neurodegenerative diseases. Neurotoxicology 2022; 88:88-101. PMID: 34748789.

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7. Cheng R, Gadde R, Fan Y, Kulkarni N, Shevale N, Bao K, Choi HS, Betharia S, Kim J. Reversal of genetic brain iron accumulation by N,N’-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice. Arch Toxicol 2022; 96(7):1951-1962. PMID: 35445828.

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8. Ekaputri S, Choi EK, Sabelli M, Aring L, Green KJ, Chang J, Bao K, Choi HS, Iwase S, Kim J, Corradini E, Pietrangelo A, Burke MD, Seo YA. A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages. Proc Natl Acad Sci U S A 2022; 119(26):e2121400119. PMID: 35737834.

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9. Park SH, Kim RS, Stiles WR, Jo M, Zeng L, Rho S, Baek Y, Kim J, Kim MS, Kang H, Choi HS. Injectable thermosensitive hydrogels for a sustained release of iron nanochelators. Adv Sci 2022; e2200872. PMID: 35343104.

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10. Menon AV, Kim J. Iron promotes cardiac doxorubicin retention and toxicity through downregulation of the mitochondrial exporter ABCB8. Front Pharmacol 2022; 13:817951. PMID: 35359834.

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11. Han M, Böhlke M, Maher TJ, Kim J. Alcohol exposure increases manganese accumulation in the brain and exacerbates manganese-induced neurotoxicity in mice. Arch Toxicol 2021; 95(12):3665-3679. PMID: 34590183.

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12. Padmakumar S, Jones G, Khorkova O, Hsiao J, Kim J, Bleier BS, Amiji MM. Osmotic core-shell polymeric implant for sustained BDNF AntagoNAT delivery in CNS using minimally invasive nasal depot (MIND) approach. Biomaterials 2021; 276:120989. PMID: 34252799.

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13. Padmakumar S, Jones G, Pawar G, Khorkova O, Hsiao J, Kim J, Amiji MM, Bleier BS. Minimally Invasive Nasal Depot (MIND) Technique for Direct BDNF AntagoNAT Delivery to the Brain. J Control Release 2021; 331:176-186. PMID: 33484777.

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14. Turman JM, Cheplowitz AM, Tiwai C, Thomas T, Joshi D, Bhat M, Wu Q, Pong E, Chu SY, Szymkowski DE, Sharma A, Seveau S, Robinson JM, Kwiek JJ, Burton D, Rajaram MVS, Kim J, Hangartner L, Ganesan LP.

Accelerated clearance and degradation of cell free HIV by neutralizing antibodies occurs via FcγRIIb on liver sinusoidal endothelial cells by endocytosis. J Immunol 2021; 206(6):1284-1296. PMID: 33568400.

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15. Debreli Coskun M, Kim J. Chapter 1: Route of Administration, Distribution, and Tissue Specific Challenges. In Organelle and Molecular Targeting. 2021; Ed. Milane L, Amiji MM. CRC Press.

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16. Jones G, Goswami SK, Kang H, Choi HS, Kim J. Combating iron overload: A case for deferoxamine-based nanochelators. Nanomedicine 2020; 15:1341-1356. PMID: 32429801.

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17. Dhaliwal HK, Fan Y, Kim J, Amiji MM. Intranasal Delivery and Transfection of mRNA Therapeutics in the Brain Using Cationic Liposomes. Mol Pharm 2020; 17(6):1996-2005. PMID: 32365295.

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18. Gleba J, Kim J. A Mechanism Based Forensic Investigation into the Postmortem Redistribution of Morphine. J Anal Toxicol 2020; 44(3):256-262. PMID: 31776575.

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19. Kang H, Han M, Xue J, Baek Y, Chang J, Hu S, Nam HY, Jo M, El Fakhri G, Hutchens MP, Choi HS, Kim J. Renal clearable nanochelators for iron overload therapy. Nat Commun 2019; 10(1):5134. PMID: 31723130.

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20. Fan Y, Dhaliwal HK, Menon AV, Chang J, Choi JE, Amiji MM, Kim J. Site-specific intestinal DMT1 silencing to mitigate iron absorption using pH-sensitive multi-compartmental nanoparticulate oral delivery system. Nanomedicine 2019; 22:102091. PMID: 31626992.

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21. Ye Q, Trivedi M, Zhang Y, Böhlke M, Alsulimani HH, Chang J, Maher TJ, Deth RC, Kim J. Brain iron loading impairs DNA methylation and alters GABAergic function in mice. FASEB J 2019; 32:2460-2471. PMID: 30277817.

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22. Sukumaran A, Chang J, Han M, Mintri S, Khaw BA, Kim J. Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis. Sci Rep 2017; 7:5756. PMID: 28720890.

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23. Grillo AS, SantaMaria AM, Kafina MD, Huston NC, Cioffi AG, Huston NC, Han M, Seo YA, Yien YY, Nardone C, Menon AV, Fan J, Svoboda DC, Anderson JB, Hong JD, Nicolau BG, Subedi K, Gewirth AA, Wessling-Resnick M, Kim J, Paw BH, Burke MD. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals. Science 2017; 356:608-616. PMID: 28495746.

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24. Han M, Chang J, Kim J. Loss of divalent metal transporter 1 (DMT1) function promotes brain copper accumulation and increases impulsivity. J Neurochem 2016; 138:918-928. PMID: 27331785.

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25. Alsulimani HH, Kim J, Sani SN. Microdialysis-directed Intra-tumor Pharmacokinetic Modeling of Methotrexate in Mice and Humans. J Pharm Pharm Sci 2016; 19(2):239-251. PMID: 27518173.

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26. Ye Q, Kim J. Mutation in HFE gene decreases manganese accumulation and oxidative stress in the brain after olfactory manganese exposure. Metallomics 2016; 8: 618-627. PMID: 27295312.

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27. Menon AV, Chang J, Kim J. Mechanisms of divalent metal toxicity in affective disorders. Toxicology 2016; 339:58-72. PMID: 26551072.

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28. Alsulimani HH, Ye Q, Kim J. Effect of Hfe deficiency on memory capacity and motor coordination after manganese exposure by drinking water in mice. Toxicol Res 2015; 31(4): 347-354. PMID: 26877837.

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29. Ye Q, Kim J. Effect of olfactory manganese exposure on anxiety-related behavior in a mouse model of hemochromatosis. Environ Toxicol Pharmacol 2015; 40(1):333-341. PMID: 26189056.

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30. Ye Q, Kim J. Loss of Hfe function reverses impaired recognition memory caused by olfactory manganese exposure in mice. Toxicol Res 2015; 31(1):17-23. PMID: 25874029.

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31. Han M, Kim J. Effect of dietary iron loading on recognition memory in growing rats. PLoS One 2015; 10:e0120609. PMID: 25746420.

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32. Chang J, Kueon C, Kim J. Influence of lead on repetitive behavior and dopamine metabolism in a mouse model of iron overload. Toxicol Res 2014; 30(4):267-276. PMID: 25584146.

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33. Kim J, Wessling-Resnick M. Iron and Mechanisms of Emotional Behavior. J Nutr Biochem 2014; 25:1101-1107. PMID: 25154570.

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34. Kim J, Buckett PD, Wessling-Resnick M. Absorption of manganese and iron in a mouse model of hemochromatosis. PLoS One 2013; 8:e64944. PMID: 23705020.

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35. Kim J, Jia X, Buckett PD, Liu S, Lee C-H, Wessling-Resnick M. Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia. FASEB J 2013; 27:1657-1663. PMID: 23241313.

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36. Kim J, Wessling-Resnick M. The role of iron metabolism in lung inflammation and injury. J Aller Ther 2012; S4:004. PMID: 29226014.

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37. Kim J, Li Y, Buckett PD, Böhlke M, Thompson KJ, Takahashi M, Maher TJ, Wessling-Resnick M. Iron-responsive olfactory uptake of manganese improves motor function deficits associated with iron deficiency. PLoS One 2012; 7:e33533. PMID: 22479410.

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38. Ganesan LP, Mohanty S, Kim J, Clark KR, Robinson JM, Anderson CL. Rapid and efficient clearance of blood-borne virus by liver sinusoidal endothelium. PLoS Pathog 2011; 7: e1002281. PMID: 21980295.

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39. Kim J, Molina RM, Donaghey TC, Buckett PD, Brain JD, Wessling-Resnick M. Influence of DMT1 and iron status on inflammatory responses in the lung. Am J Physiol Lung Mol Physiol 2011; 300:L659-L665. PMID: 21278260.

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40. Kim J, Mohanty S, Ganesan LP, Hua K, Jarjoura D, Hayton WL, Robinson JM, Anderson CL. FcRn in the yolk sac endoderm of mouse is required for IgG transport to fetus. J Immunol 2009; 182:2583-2589. PMID: 19234152.

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41. Kim J, Bronson CL, Wani MA, Oberyszyn TM, Mohanty S, Chaudhury C, Hayton WL, Robinson JM, Anderson CL. β2-microglobulin deficient mice catabolize IgG more rapidly than FcRn-α-chain deficient mice. Exp Biol Med 2008; 233:603-609. PMID: 18375831.

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42. Kim J, Hayton WL, Robinson JM, Anderson CL. Kinetics of FcRn-mediated recycling of IgG and albumin in human: Pathophysiology and therapeutic implications using a simplified mechanism-based model. Clin Immunol 2007; 122:146-155. PMID: 17046328.

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43. Kim J, Hayton WL, Schultz IR. Modeling the brain-pituitary-gonad axis in salmon. Mar Environ Res 2006; 62:S426-S432. PMID: 16716390.

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44. Wani MA, Haynes L, Kim J, Bronson CL, Chaudhury C, Mohanty S, Waldmann TA, Robinson JM, Anderson CL. Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant β2-microglobulin gene. Proc Natl Acad Sci U S A 2006; 103:5084-5089. PMID: 16549777.

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45. Kim J, Bronson CL, Hayton WL, Radmacher MD, Roopenian DC, Robinson JM, Anderson CL. Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces. Am J Physiol: GI Liver Physiol 2006; 290:G352-G360. PMID: 16210471.

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46. Kim J, Kim EJ, Han KS, Chang MS, Lee MG. Gastrointestinal first-pass effect of YJA-20379-8, a new reversible proton pump inhibitor, in rats. J Pharm Pharmacol 1999; 51:1031-1036. PMID: 10528986.

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47. Kim J, Kim SH, Lee MG. Liver and gastrointestinal first-pass effects of azosemide in rats. J Pharm Pharmacol 1997; 49:878-883. PMID: 9306255.

48.Dhorajia V, Kim J, Kim Y. Early adaptive responses in the skeletal muscle of young mice with hereditary hemochromatosis. Mol Biol Rep 2023; 50:3179–3187. PMID: 36701040.